Circeif4g3
WebNov 16, 2024 · Overexpressing SRRM4, known for regulating ME inclusion in mRNAs critical for neural differentiation, in human HEK293 cells resulted in the biogenesis of over 2000 novel ME-circRNAs, including ME-circEIF4G3, and changes in the abundance of many canonical circRNAs, including circSETDB2 and circLRBA. This shows SRRM4, in … WebCircEIF4G3 acts as a scaffold to promote δ-catenin ubiquitin degradation by TRIM25. (A) The expression of δ-catenin protein in GC cells with or without circEIF4G3 overexpression after treatment...
Circeif4g3
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WebJul 2, 2024 · Mechanistic studies revealed that circEIF4G3 bound to \u03b4-catenin protein to promote its TRIM25-mediated ubiquitin degradation and interacted with miR-4449 to … WebFeb 2, 2024 · Renal cell carcinoma (RCC) is one of the top ten tumors over the world. RCC is not sensitive to radiotherapy and chemotherapy. Therefore, it is necessary to find new targets for the treatment. CircRNAs are a special type of noncoding RNAs, which play important roles in many types of cancer. In this study, we found circ_000558 was …
WebJul 2, 2024 · CircEIF4G3 expression was downregulated in patients with GC and predicted poor prognosis. CircEIF4G3 destabilized δ-catenin by forming circEIF4G3/δ … WebAug 10, 2024 · The formation of a unique back-splice junction (BSJ) differentiates the circRNAs from their linear counterpart. CircRNAs are highly expressed in the central nervous system where many of them are regulated during development 1 – 3, inflammation 4, and also found to function as biomarkers in cancer 5 – 7.
WebJul 2, 2024 · Overexpression of circEIF4G3 suppressed GC growth and metastasis through the inhibition of \u03b2-catenin signaling, whereas knockdown of circEIF4G3 showed the opposite effects. Mechanistic studies revealed that circEIF4G3 bound to \u03b4-catenin protein to promote its TRIM25-mediated ubiquitin degradation and interacted with miR … WebDownload scientific diagram CircEIF4G3 functions as a miR-4449 sponge. (A) RIP assay was applied using Ago2 antibody in GC cells. The relative RNA level of circEIF4G3 was detected by qRT-PCR.
WebBiogenesis Inc me circrna biogenesis factor Me Circrna Biogenesis Factor, supplied by Biogenesis Inc, used in various techniques. Bioz Stars score: 92/100, based on 3 PubMed citations.
Web(A) Cell counting assays for control and circEIF4G3 overexpressing GC cells. (B) The impact of circEIF4G3 overexpression on GC cell proliferation was determined by cell colony formation assay. how do touch screens work on phonesWebCircEIF4G3 destabilizes δ-catenin protein and inactivates β-catenin signaling. (A) TRAP experiment and LC-MS/MS analysis. GST protein expression was detected by western blot. δ-catenin protein... how much snow did indianapolis get todayWebBackground: Circular RNAs (circRNAs), a new group of endogenous non-coding RNAs, plays a crucial role in various types of carcinomas. However, there is still limited … how do touchscreens workWeb正式实验上，团队构建了circEIF4G3敲低与过表达的细胞模型，通过体外功能实验（RNA-FISH、细胞增殖与迁移和侵袭检测、细胞凋亡检测）以及体内动物实验（免疫组织化学 … how do tourist reserve their accommodationWebAug 22, 2024 · This study found that CircEIF4G3 was down-regulated in gastric cancer patients and predicted poor prognosis. CircEIF4G3 destabilizes δ-catenin by forming a … how much snow did indianapolis getWebJul 2, 2024 · Europe PMC is an archive of life sciences journal literature. how do toupees stay onWebCircEIF4G3 is downregulated in GC. (A) GEO datasets were downloaded for integrated analyses of differentially expressed circRNAs. The common downregulated circRNAs were listed as indicated. (B)... how much snow did indianapolis get yesterday