WebApr 17, 2024 · The PACIFIC study [NCT02125461] was a phase 3, randomized, placebo-controlled study of patients with stage III [locally advanced, unresectable non–small cell lung cancer] who did not progress after definitive chemo-radiotherapy and were 18 or older, performance status 1, life expectancy 12 weeks or more, all-comers population, 1 to 42 … WebThe staging system for lung cancer has recently been revised through the International Association for Study of Lung Diagnosis and staging Cancer (IASLC). ... Treatment with erlotinib may be recommended as toxicity for cisplatin/pemetrexed in patients with third-line therapy for patients with performance sta- non-squamous histology, in ...
Alimta: Uses, Dosage, Side Effects, Warnings - Drugs.com
WebPemetrexed and cisplatin is a combination of two chemotherapy drugs. Pemetrexed is also called Alimta. You might have it as a treatment for non small cell lung cancer … WebConclusion: Pemetrexed plus platinum doublet regimen is an efficacious treatment for advanced nonsquamous NSCLC patients. Our findings support the use of pemetrexed plus platinum doublet regimen as first-line treatment in advanced nonsquamous NSCLC patients because of its potential survival benefits. Keywords: chemotherapy-naive, lung cancer ... mayer blazers twitter
Pemetrexed and cisplatin with concurrent radiotherapy for locally ...
WebObjectives: SPECTRA is a multicenter, randomized phase II study of chemotherapy with cisplatin (CDDP) plus S-1 versus CDDP plus pemetrexed (PEM) in combination with … WebApr 4, 2024 · Eligible patients with previously untreated metastatic nonsquamous non–small-cell lung cancer without EGFR/ALK alterations were randomly assigned 2:1 to … WebBackground. Acquired resistance to EGFR TKI remains a significant barrier for patients with EGFR-mutated lung cancer, especially for those without acquired EGFR T790M.The current study explored the safety and efficacy of combinational treatment with atezolizumab, bevacizumab, and pemetrexed-platinum in patients with EGFR-mutated NSCLC after … hershey\u0027s dark chocolate syrup